Recommendations for the diagnosis and management of persons with suspected vaccine-induced immune thrombotic thrombocytopenia (VITT)

Nancy Yomayusa, Juan Acevedo, Virginia Abello Polo, Raúl Izaguirre, Carlos Ramírez, María Helena Solano, Sergio Ramírez, Patricia Rodríguez, Lina Morón, Ilich De la Hoz, Kelly Rocio Chacón, Paula Gutiérrez, Claudia Agudelo, Sonia Hernández, Guillermo León, José Accini, Guillermo Ortíz, Alejandro Concha-Mejia, Rubén Contreras, Bibiana Escobar, Tatiana Espinosa, Camilo González, Erica Yama, Gustavo Aroca, Cecilia Guillermo, Otto Hamann, Laura Horlandy, Claudia Moreno, Natalia Mejía, Fernán Mendoza, Jeffrey Castellanos, Jose Rozo, Camilo Montero, José Navarro, José Oñate, Diego Pinto, Natalia Restrepo, Oscar Saenz, Lina Triana, Liliana Correa, Luis Sabbagh, Ana Castillo, Rodolfo Torres, Alberto Lineros


In recent months, rare cases of thrombosis at unusual sites associated with thrombocytopenia, occurring within a typical risk window (i.e., 4-28 days) after receiving SARS CoV2 vaccines, have been reported. Healthcare professionals should be prepared to detect these cases on time. The Expert Panel of the Knowledge Management and Transfer Network conducted a free search of the related literature. With the available information and the clinical expertise of the working group, we formulated, reviewed, and endorsed recommendations for the timely suspicion, diagnosis (case definitions, the use of initial laboratory and imaging tests, specific tests), and management of these thrombotic conditions. This document is considered a living document that will be updated as new evidence emerges, and recommendations may change over time.

Palabras clave

Thrombocytopenia; COVID-19 Vaccines; Thrombosis

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