Systematic review: The potency of Zataria multiflora Boiss in treatment of vaginal infections

Mohaddese Mahboubi Mahboubi

Resumen


Vaginitis as female infectious disease is accompanied with some clinical symptoms such as vaginal abnormal discharges, itching, burning and many other unpleasant signs in patients. The responsable microorganisms in vaginitis are belonged to different kind of microorganisms including bacteria (Gardenella vaginitis), yeast (Candida albicans) and protozoa (Trichomonas vaginalis). The current treatments of these infections are chemical oral and vaginal drugs with many adverse effects for patients. Furthermore, appearance of resistant microorganisms to these drugs has intensified the treatment’s problem. The aim of this review article was to evaluate the potency of “Zataria multiflora” essential oil in treatment of women’s vaginitis. For preparing this manuscript, the information was extracted from different electronic and published resources. Investigation in different resources showed there were 6 clinical trials that evaluate it as suitable treatment for vaginitis. 5 clinical studies have been focused on 0.1% Z. multiflora essential oils in treatment of bacterial vaginosis (n=1), candidiasis (n=1) and trichomoniasis (n=1). Two clinical studies were related to treatments of bacterial vaginosis, trichomoniasis and mixed infection. There is one clinical study for treatment of candidiasis by 1% Z. multiflora methanol extract. Z. multiflora was formulated in cream form and applied for 5-7 continuous days. The results of clinical trials showed that Z. multiflora essential oil (0.1%) can be used as safe and efficient alternative treatment for treatment of bacterial vaginosis, candidiasis and to a lesser extent for trichomoniasis.


Palabras clave


Zataria multiflora; essential oil; Candidiasis; Bacterial vaginosis; trichomoniasis

Texto completo:

PDF (English)


DOI: http://dx.doi.org/10.22354/in.v22i2.712

Enlaces refback

  • No hay ningún enlace refback.


Kra 15 N 118-03 oficina 503, Bogotá D.C., ColombiaTeléfonos: 215 37 14 - 215 35 17 acin@acin.org Infectio es una publicación científica, órgano oficial de la Asociación Colombiana de Infectología, ACIN. La revista no se responsabiliza por los criterios expresados por sus autores. www.revistainfectio.org; La Revista Infectio se encuentra indexada en Scielo, Flying Publisher, Publimdex, Imbiomed, Doaj, Lilacs