Guía de práctica clínica para la prevención de la infección del sitio quirúrgico

Contenido principal del artículo

Jorge Alberto Cortés
Martha Carolina Valderrama-Rios
Lilian Torregrosa-Almonacid
Cándida Diaz-Brochero
Laura Cristina Nocua-Báez
Erika Paola Vergara
Felipe Vargas-Barato
Bibiana Jeannette Escobar
Oscar A. Guevara
Julián Mauricio Parada
Oscar Alberto Velásquez
Mauricio Zuluaga Botero
Carlos Oliver Valderrama-Molina
Carlos Fernando Grillo-Ardila
German Esparza
Karina María Vélez
Rosibel Prieto-Silva

Resumen

Las infecciones asociadas a la atención de la salud (IAAS) son el evento adverso más frecuentemente reportado en todo el mundo, siendo la infección del sitio quirúrgico (ISQ) la IAAS con mayor incidencia en los países de ingresos bajos y medios, como Colombia, con consecuencias importantes para los pacientes, la sociedad y el sistema de salud, debido al incremento en morbilidad, mortalidad y costos que genera. La presente guía contiene recomendaciones perioperatorias para la prevención de la ISQ, basadas en la evidencia, realizadas mediante el proceso de adaptación de guías de práctica clínica para el contexto colombiano.

Detalles del artículo

Sección
Guias de Práctica Clínica

Citas

Collins AS. Preventing Health Care-Associated Infections. BTI - Patient Safety and Quality: An Evidence-Based Handbook for Nurses.

Brennan TA, Leape LL, Laird NM, Hebert L, Localio AR, Lawthers AG, et al. Incidence of adverse events and negligence in hospitalized patients. Results of the Harvard Medical Practice Study I. N Engl J Med 1991; 324: 370-6.

https://doi.org/10.1056/NEJM199102073240604

Leape LL, Brennan TA, Laird N, Lawthers AG, Localio AR, Barnes BA, et al. The nature of adverse events in hospitalized patients. Results of the Harvard Medical Practice Study II. N Engl J Med 1991; 324: 377-84.

https://doi.org/10.1056/NEJM199102073240605

Vincent J-L, Rello J, Marshall J, Silva E, Anzueto A, Martin CD, et al. International Study of the Prevalence and Outcomes of Infection in Intensive Care Units. JAMA 2009; 302: 2323-9. https://doi.org/10.1001/jama.2009.1754

Allegranzi B, Bagheri Nejad S, Combescure C, Graafmans W, Attar H, Donaldson L, et al. Burden of endemic health-care-associated infection in developing countries: systematic review and meta-analysis. Lancet 2011; 377: 228-41.

https://doi.org/10.1016/S0140-6736(10)61458-4

World Alliance for Patient Safety: Forward programme 2005. Geneva: World Health Organization; 2004 (https://www.who.int/publications/i/ item/9241592443).

World Alliance for Patient Safety. Global Patient Safety Challenge 2005- 2006. Clean Care is Safer Care. Geneva: World Health Organization; 2005 (https://www.who.int/publications /i/item/9241593733).

Horan TC, Gaynes RP, Martone WJ, Jarvis WR, Emori TG. CDC definitions of nosocomial surgical site infections, 1992: a modification of CDC definitions of surgical wound infections. Infect Control Hosp Epidemiol 1992; 13: 606-8.

https://doi.org/10.2307/30148464

Huerta-Gutierrez R, Braga L, Camacho-Ortiz A, Diaz-Ponce H, Garcia- Mollinedo L, Guzman-Blanco M, et al. One-day point prevalence of healthcare-associated infections and antimicrobial use in four countries in Latin America. Int J Infect Dis 2019; 86: 157-66. https://doi.org/10.1016/j.ijid.2019.06.016

World Health Organization. Report on the burden of endemic health care-associated infection worldwide. Geneva: World Health Organization; 2011 (https://apps.who.int/iris/ bitstream/ handle/10665/8013/9789241501507_eng.pdf?sequence=1).

Alvarez-Moreno C, Perez-Fernandez AM, Rosenthal VD, Quintero J, Chapeta-Parada E, Linares C, et al. Surgical site infection rates in 4 cities in Colombia: findings of the International Nosocomial Infection Control Consortium (INICC). Am J Infect Control 2014; 42: 1089-92. https://doi.org/10.1016/j.ajic.2014.06.010

Llanos Mendez A, Diaz Molina C, Fernandez-Crehuet Navajas R. [Surgical site infection in a tertiary hospital. A prospective surveillance study (2001-2004)]. Cir Esp 2010; 88: 319-27. https://doi.org/10.1016/S2173-5077(10)70038-7

Badia JM, Casey AL, Petrosillo N, Hudson PM, Mitchell SA, Crosby C. Impact of surgical site infection on healthcare costs and patient outcomes: a systematic review in six European countries. J Hosp Infect 2017; 96: 1-15.

https://doi.org/10.1016/j.jhin.2017.03.004

Monahan M, Jowett S, Pinkney T, Brocklehurst P, Morton DG, Abdali Z, et al. Surgical site infection and costs in low- and middle-income countries: A systematic review of the economic burden. PLoS One 2020; 15: e0232960.

https://doi.org/10.1371/journal.pone.0232960

Astagneau P, Rioux C, Golliot F, Brucker G, Group INS. Morbidity and mortality associated with surgical site infections: results from the 1997- 1999 INCISO surveillance. J Hosp Infect 2001; 48: 267-74.

https://doi.org/10.1053/jhin.2001.1003

Kirkland KB, Briggs JP, Trivette SL, Wilkinson WE, Sexton DJ. The impact of surgical-site infections in the 1990s: attributable mortality, excess length of hospitalization, and extra costs. Infect Control Hosp Epidemiol 1999; 20: 725-30.

https://doi.org/10.1086/501572

Saavedra CH, Ordonez KM, Diaz JA. [Nosocomial infections impact in a hospital in Bogota, Colombia: effects on mortality and hospital costs]. Rev Chilena Infectol 2015; 32: 25-9. https://doi.org/10.4067/S0716-10182015000200004

World Alliance for Patient Safety. The second WHO Global Patient Safety Challenge: Safe Surgery Saves Lives. Geneva: World Health Organization; 2008 https://apps.who.int/iris/bitstream/handle/10665/70080/WHO_IER_PSP_2008.07_eng.pdf?sequence=1).

World Health Organization. WHO Guidelines for Safe Surgery 2009: Safe Surgery Saves Lives Geneva: World Health Organization; 2009 (https:// apps.who.int/iris/handle/10665/ 44185).

U.S. Centers for Disease Control and Prevention. The National Healthcare Safety Network (NHSN). Patient Safety Component Manual 2021.

Owens CD, Stoessel K. Surgical site infections: epidemiology, microbiology and prevention. J Hosp Infect 2008; 70 Suppl 2: 3-10. https://doi.org/10.1016/S0195-6701(08)60017-1

Cheadle WG. Risk factors for surgical site infection. Surg Infect (Larchmt) 2006; 7 Suppl 1: S7-11.

https://doi.org/10.1089/sur.2006.7.s1-7

Li X, Nylander W, Smith T, Han S, Gunnar W. Risk Factors and Predictive Model Development of Thirty-Day Post- Operative Surgical Site Infection in the Veterans Administration Surgical Population. Surg Infect (Larchmt) 2018; 19: 278-85.

https://doi.org/10.1089/sur.2017.283

Anderson DJ, Podgorny K, Berrios-Torres SI, Bratzler DW, Dellinger EP, Greene L, et al. Strategies to prevent surgical site infections in acute care hospitals: 2014 update. Infect Control Hosp Epidemiol 2014; 35: 605-27.

https://doi.org/10.1086/676022

Implementation manual to support the prevention of surgical site infections at the facility level - turning recommendations into practice (interim version). Geneva: World Health Organization; 2018 (WHO/HIS/ SDS/2018.18).

Colombia. Ministerio de Salud y Protección Social. Guía Metodológica, Adopción Adaptación de Guías de Práctica Clínica Basadas en Evidencia. Guía metodológica en Internet. Edición 1ª. Bogotá DC. 2017, Disponible en gpc.minsalud.gov.co.

Brouwers MC, Kho ME, Browman GP, Burgers JS, Cluzeau F, Feder G, et al. AGREE II: advancing guideline development, reporting and evaluation in health care. CMAJ 2010; 182: E839-42. https://doi.org/10.1503/cmaj.090449

Global guidelines for the prevention of surgical site infection, second edition. Geneva: World Health Organization; 2018. Licence: CC BY-NC-SA 3.0 IGO.

Surgical site infections: prevention and treatment NICE guideline [NG125]. 2019.

Schunemann HJ, Wiercioch W, Brozek J, Etxeandia-Ikobaltzeta I, Mustafa RA, Manja V, et al. GRADE Evidence to Decision (EtD) frameworks for adoption, adaptation, and de novo development of trustworthy recommendations: GRADE-ADOLOPMENT. J Clin Epidemiol 2017

https://doi.org/10.1016/j.jclinepi.2016.09.00981: 101-10. https://doi.org/10.1088/1475-7516/2016/09/009

Schunemann HJ, Mustafa R, Brozek J, Santesso N, Alonso-Coello P, Guyatt G, et al. GRADE Guidelines: 16. GRADE evidence to decision frameworks for tests in clinical practice and public health. J Clin Epidemiol 2016; 76: 89-98.

https://doi.org/10.1016/j.jclinepi.2016.01.032

Balshem H, Helfand M, Schunemann HJ, Oxman AD, Kunz R, Brozek J, et al. GRADE guidelines: 3. Rating the quality of evidence. J Clin Epidemiol 2011; 64: 401-6. https://doi.org/10.1016/j.jclinepi.2010.07.015

Gutierrez GC, Pulido Álvarez AC, de la Hoz AM, Alviar KM, Muñoz Velandia ÓM, Guerrero Carvajar R, et al. Guía Metodológica para la elaboración de Guías de Práctica Clínica con Evaluación Económica en el Sistema General de Seguridad Social en Salud Colombiano Bogotá DC: Fundación Santa Fe de Bogotá - Centro de Estudios e Investigación en Salud; 2014.

Andrews J, Guyatt G, Oxman AD, Alderson P, Dahm P, Falck-Ytter Y, et al. GRADE guidelines: 14. Going from evidence to recommendations: the significance and presentation of recommendations. J Clin Epidemiol 2013; 66: 719-25.

https://doi.org/10.1016/j.jclinepi.2012.03.013

Culebras JM. Malnutrition in the twenty-first century: an epidemic affecting surgical outcome. Surg Infect (Larchmt) 2013; 14: 237-43. https://doi.org/10.1089/sur.2013.9993

Mainous MR, Deitch EA. Nutrition and infection. Surg Clin North Am 1994; 74: 659-76.

https://doi.org/10.1016/S0039-6109(16)46335-8

Culebras-Fernandez JM, de Paz-Arias R, Jorquera-Plaza F, Garcia de Lorenzo A. [Nutrition in the surgical patient: immunonutrition]. Nutr Hosp 2001; 16: 67-77.

Mazaki T, Ishii Y, Murai I. Immunoenhancing enteral and parenteral nutrition for gastrointestinal surgery: a multiple-treatments meta-analysis. Ann Surg 2015; 261: 662-9. https://doi.org/10.1097/SLA.0000000000000935

Yue C, Tian W, Wang W, Huang Q, Zhao R, Zhao Y, et al. The impact of perioperative glutamine-supplemented parenteral nutrition on outcomes of patients undergoing abdominal surgery: a meta-analysis of randomized clinical trials. Am Surg 2013; 79: 506-13. https://doi.org/10.1177/000313481307900527

Di Carlo V, Gianotti L, Balzano G, Zerbi A, Braga M. Complications of pancreatic surgery and the role of perioperative nutrition. Dig Surg 1999; 16: 320-6. https://doi.org/10.1159/000018742

Global Guidelines for the Prevention of Surgical Site Infection. Geneva2018.

Casas-Rodera P, Gomez-Candela C, Benitez S, Mateo R, Armero M, Castillo R, et al. Immunoenhanced enteral nutrition formulas in head and neck cancer surgery: a prospective, randomized clinical trial. Nutr Hosp 2008; 23: 105-10.

de Luis DA, Aller R, Izaola O, Cuellar L, Terroba MC. Postsurgery enteral nutrition in head and neck cancer patients. Eur J Clin Nutr 2002; 56: 1126- 9. https://doi.org/10.1038/sj.ejcn.1601458

de Luis DA, Izaola O, Cuellar L, Terroba MC, Aller R. Randomized clinical trial with an enteral arginine-enhanced formula in early postsurgical head and neck cancer patients. Eur J Clin Nutr 2004; 58: 1505-8.

https://doi.org/10.1038/sj.ejcn.1601999

de Luis DA, Izaola O, Cuellar L, Terroba MC, Martin T, Aller R. Clinical and biochemical outcomes after a randomized trial with a high dose of enteral arginine formula in postsurgical head and neck cancer patients. Eur J Clin Nutr 2007; 61: 200-4.

https://doi.org/10.1038/sj.ejcn.1602515

Tepaske R, te Velthuis H, Oudemans-van Straaten HM, Bossuyt PM, Schultz MJ, Eijsman L, et al. Glycine does not add to the beneficial effects of perioperative oral immune-enhancing nutrition supplements in high- risk cardiac surgery patients. JPEN J Parenter Enteral Nutr 2007; 31: 173- 80. https://doi.org/10.1177/0148607107031003173

Okabayashi T, Nishimori I, Sugimoto T, Maeda H, Dabanaka K, Onishi S, et al. Effects of branched-chain amino acids-enriched nutrient support for patients undergoing liver resection for hepatocellular carcinoma. J Gastroenterol Hepatol 2008

https://doi.org/10.1111/j.1440- 1746.2008.05504.x

Celik JB, Gezginc K, Ozcelik K, Celik C. The role of immunonutrition in gynecologic oncologic surgery. Eur J Gynaecol Oncol 2009; 30: 418-21.

Falewee MN, Schilf A, Boufflers E, Cartier C, Bachmann P, Pressoir M, et al. Reduced infections with perioperative immunonutrition in head and neck cancer: exploratory results of a multicenter, prospective, randomized, double-blind study. Clin Nutr 2014; 33: 776-84. https://doi.org/10.1016/j.clnu.2013.10.006

Fujitani K, Tsujinaka T, Fujita J, Miyashiro I, Imamura H, Kimura Y, et al. Prospective randomized trial of preoperative enteral immunonutrition followed by elective total gastrectomy for gastric cancer. Br J Surg 2012; 99: 621-9.

https://doi.org/10.1002/bjs.8706

Gianotti L, Braga M, Nespoli L, Radaelli G, Beneduce A, Di Carlo V. A randomized controlled trial of preoperative oral supplementation with a specialized diet in patients with gastrointestinal cancer. Gastroenterology 2002; 122: 1763-70.

https://doi.org/10.1053/gast.2002.33587

Klek S, Sierzega M, Szybinski P, Szczepanek K, Scislo L, Walewska E, et al. The immunomodulating enteral nutrition in malnourished surgical patients - a prospective, randomized, double-blind clinical trial. Clin Nutr 2011; 30: 282-8.

https://doi.org/10.1016/j.clnu.2010.10.001

Snyderman CH, Kachman K, Molseed L, Wagner R, D'Amico F, Bumpous J, et al. Reduced postoperative infections with animmune-enhancing nutritional supplement. Laryngoscope 1999; 109: 915-21.

https://doi.org/10.1097/00005537-199906000-00014

Tepaske R, Velthuis H, Oudemans-van Straaten HM, Heisterkamp SH, van Deventer SJ, Ince C, et al. Effect of preoperative oral immune-enhancing nutritional supplement on patients at high risk of infection after cardiac surgery: a randomised placebo-controlled trial. Lancet 2001; 358: 696- 701. https://doi.org/10.1016/S0140-6736(01)05836-6

Horie H, Okada M, Kojima M, Nagai H. Favorable effects of preoperative enteral immunonutrition on a surgical site infection in patients with colorectal cancer without malnutrition. Surg Today 2006; 36: 1063-8.

https://doi.org/10.1007/s00595-006-3320-8

Takeuchi H, Ikeuchi S, Kawaguchi Y, Kitagawa Y, Isobe Y, Kubochi K, et al. Clinical significance of perioperative immunonutrition for patients with esophageal cancer. World J Surg 2007; 31: 2160-7.

https://doi.org/10.1007/s00268-007-9219-8

De Luis DA, Izaola O, Castro A, Martin M, Torres B, Lopez Gomez J, et al. [Study of tolerance and aceptability of a hyperproteic enteral formula enriched in fiber]. Nutr Hosp 2014; 31: 326-33.

Ramirez Galleymore P, Viera V. Preoperative skin antisepsis. Med Intensiva (Engl Ed) 2019; 43 Suppl 1: 18-22.

https://doi.org/10.1016/j.medin.2018.07.019

Targeted literature review: What are the key infection prevention and control recommendations to inform a surgical site infection (SSI) prevention quality improvement tool? Edinburgh: Health Protection Scotland; version 3.0, February 2015 (http://www.documents.hps.scot.nhs. uk/hai/infection-control/evidence-for-carebundles/literature-reviews/ ssi-review-2015-02.pdf, accessed 12 March 2023).

Owens P, McHugh S, Clarke-Moloney M, Healy D, Fitzpatrick F, McCormick P, et al. Improving surgical site infection prevention practices through a multifaceted educational intervention. Ir Med J 2015; 108: 78-81.

Kaiser AB, Kernodle DS, Barg NL, Petracek MR. Influence of preoperative showers on staphylococcal skin colonization: a comparative trial of antiseptic skin cleansers. Ann Thorac Surg 1988; 45: 35-8.

https://doi.org/10.1016/S0003-4975(10)62391-0

Seal LA, Paul-Cheadle D. A systems approach to preoperative surgical patient skin preparation. Am J Infect Control 2004; 32: 57-62. https://doi.org/10.1016/j.ajic.2003.11.001

Krautheim AB, Jermann TH, Bircher AJ. Chlorhexidine anaphylaxis: case report and review of the literature. Contact Dermatitis 2004; 50: 113-6. https://doi.org/10.1111/j.0105-1873.2004.00308.x

Byrne DJ, Phillips G, Napier A, Cuschieri A. The effect of whole body disinfection on intraoperative wound contamination. J Hosp Infect 1991; 18: 145-8. https://doi.org/10.1016/0195-6701(91)90159-6

Earnshaw JJ, Berridge DC, Slack RC, Makin GS, Hopkinson BR. Do preoperative chlorhexidine baths reduce the risk of infection after vascular reconstruction? Eur J Vasc Surg 1989; 3: 323-6. https://doi.org/10.1016/S0950-821X(89)80068-4

Hayek LJ, Emerson JM. Preoperative whole body disinfection--a controlled clinical study. J Hosp Infect 1988; 11 Suppl B: 15-9. https://doi.org/10.1016/0195-6701(88)90151-X

Lynch W, Davey PG, Malek M, Byrne DJ, Napier A. Cost-effectiveness analysis of the use of chlorhexidine detergent in preoperative whole-body disinfection in wound infection prophylaxis. J Hosp Infect 1992; 21: 179- 91.

https://doi.org/10.1016/0195-6701(92)90074-V

Randall PE, Ganguli LA, Keaney MG, Marcuson RW. Prevention of wound infection following vasectomy. Br J Urol 1985; 57: 227-9. https://doi.org/10.1111/j.1464-410X.1985.tb06430.x

Rotter ML. A placebo-controlled trial of the effect of two preoperative baths or showers with chlorhexidine detergent on postoperative wound infection rates. J Hosp Infect 1988; 12: 137-8. https://doi.org/10.1016/0195-6701(88)90142-9

Veiga DF, Damasceno CA, Veiga-Filho J, Figueiras RG, Vieira RB, Garcia ES, et al. Randomized controlled trial of the effectiveness of chlorhexidine showers before elective plastic surgical procedures. Infect Control Hosp Epidemiol 2009; 30: 77-9. https://doi.org/10.1086/592980

Ayliffe GA, Noy MF, Babb JR, Davies JG, Jackson J. A comparison of pre- operative bathing with chlorhexidine-detergent and non-medicated soap in the prevention of wound infection. J Hosp Infect 1983; 4: 237-44. https://doi.org/10.1016/0195-6701(83)90024-5

Leigh DA, Stronge JL, Marriner J, Sedgwick J. Total body bathing with 'Hibiscrub' (chlorhexidine) in surgical patients: a controlled trial. J Hosp Infect 1983; 4: 229-35. https://doi.org/10.1016/0195-6701(83)90023-3

Graling PR, Vasaly FW. Effectiveness of 2% CHG cloth bathing for reducing surgical site infections. AORN J 2013; 97: 547-51. https://doi.org/10.1016/j.aorn.2013.02.009

Johnson AJ, Daley JA, Zywiel MG, Delanois RE, Mont MA. Preoperative chlorhexidine preparation and the incidence of surgical site infections after hip arthroplasty. J Arthroplasty 2010; 25: 98-102. https://doi.org/10.1016/j.arth.2010.04.012

Johnson AJ, Kapadia BH, Daley JA, Molina CB, Mont MA. Chlorhexidine reduces infections in knee arthroplasty. J Knee Surg 2013; 26: 213-8. https://doi.org/10.1055/s-0032-1329232

van Dijk HFG, Verbrugh HA, Ad hoc advisory committee on disinfectants of the Health Council of the N. Resisting disinfectants. Commun Med (Lond) 2022; 2: 6. https://doi.org/10.1038/s43856-021-00070-8

Webster J, Osborne S. Preoperative bathing or showering with skin antiseptics to prevent surgical site infection. Cochrane Database Syst Rev 2015: CD004985. https://doi.org/10.1002/14651858.CD004985.pub5

Tanner J, Melen K. Preoperative hair removal to reduce surgical site infection. Cochrane Database Syst Rev 2021; 8: CD004122. https://doi.org/10.1002/14651858.CD004122.pub5

Jolivet S, Lucet JC. Surgical field and skin preparation. Orthop Traumatol Surg Res 2019; 105: S1-S6.

https://doi.org/10.1016/j.otsr.2018.04.033

Lefebvre A, Saliou P, Lucet JC, Mimoz O, Keita-Perse O, Grandbastien B, et al. Preoperative hair removal and surgical site infections: network meta- analysis of randomized controlled trials. J Hosp Infect 2015; 91: 100-8.

https://doi.org/10.1016/j.jhin.2015.06.020

Preventing surgical site infections. Key recommendations for practice. Dublin: Joint Royal College of Surgeons in Ireland/Royal Colleges of Physicians of Ireland Working Group on Prevention of Surgical Site Infection; 2012 (https://www.rcsi.ie/files/surgery/docs 2014031 8021114_ Sample%20Audit%20Surgical%20site%20Inf.pdf, accessed 12 March 2023).

Celik SE, Kara A. Does shaving the incision site increase the infection rate after spinal surgery? Spine (Phila Pa 1976) 2007; 32: 1575-7. https://doi.org/10.1097/BRS.0b013e318074c39f

Abouzari M, Sodagari N, Hasibi M, Behzadi M, Rashidi A. Re: Nonshaved cranial surgery in black Africans: a short-term prospective preliminary study (Adeleye and Olowookere, Surg Neurol 2008;69-72) Effect of hair on surgical wound infection after cranial surgery: a 3-armed randomized clinical trial. Surg Neurol 2009; 71: 261-2; author reply 2.

https://doi.org/10.1016/j.surneu.2008.01.05

Court-Brown CM. Preoperative skin depilation and its effect on postoperative wound infections. J R Coll Surg Edinb 1981; 26: 238-41.

Horgan MA, Kernan JC, Schwartz MS, Kellogg JX, McMenomey SO, Delashaw JB. Shaveless brain surgery: safe, well tolerated, and cost effective. Skull Base Surg 1999; 9: 253-8. https://doi.org/10.1055/s-2008-1058134

Ilankovan V, Starr DG. Preoperative shaving: patient and surgeon preferences and complications for the Gillies incision. J R Coll Surg Edinb 1992; 37: 399-401.

Kattipattanapong W, Isaradisaikul S, Hanprasertpong C. Surgical site infections in ear surgery: hair removal effect; a preliminary, randomized trial study. Otolaryngol Head Neck Surg 2013; 148: 469-74.

https://doi.org/10.1177/0194599812472297

Rojanapirom S, Danchaivijitr S. Pre-operative shaving and wound infection in appendectomy. J Med Assoc Thai 1992; 75 Suppl 2: 20-3.

Alexander JW, Fischer JE, Boyajian M, Palmquist J, Morris MJ. The influence of hair-removal methods on wound infections. Arch Surg 1983; 118: 347- 52. https://doi.org/10.1001/archsurg.1983.01390030079013

Balthazar ER, Colt JD, Nichols RL. Preoperative hair removal: a random prospective study of shaving versus clipping. South Med J 1982; 75: 799- 801. https://doi.org/10.1097/00007611-198207000-00006

Grober ED, Domes T, Fanipour M, Copp JE. Preoperative hair removal on the male genitalia: clippers vs. razors. J Sex Med 2013; 10: 589-94. https://doi.org/10.1111/j.1743-6109.2012.02904.x

Adisa AO, Lawal OO, Adejuyigbe O. Evaluation of two methods of preoperative hair removal and their relationship to postoperative wound infection. J Infect Dev Ctries 2011; 5: 717-22. https://doi.org/10.3855/jidc.1527

Goeau-Brissonniere O, Coignard S, Merao AP, Haicault G, Sasako M, Patel JC. [Preoperative skin preparation. A prospective study comparing a depilatory agent in shaving]. Presse Med 1987; 16: 1517-9.

Powis SJ, Waterworth TA, Arkell DG. Preoperative skin preparation: clinical evaluation of depilatory cream. Br Med J 1976; 2: 1166-8. https://doi.org/10.1136/bmj.2.6045.1166

Seropian R, Reynolds BM. Wound infections after preoperative depilatory versus razor preparation. Am J Surg 1971; 121: 251-4. https://doi.org/10.1016/0002-9610(71)90199-1

Thur de Koos P, McComas B. Shaving versus skin depilatory cream for preoperative skin preparation. A prospective study of wound infection rates. Am J Surg 1983; 145: 377-8. https://doi.org/10.1016/0002-9610(83)90205-2

Surgical site infection: evidence update (April 2019). London: National Institute for Health and Care Excellence (NICE); 2019. https://www.nice. org.uk/guidance/ng125, accessed 13 March 2023).

Parienti JJ, Thibon P, Heller R, Le Roux Y, von Theobald P, Bensadoun H, et al. Hand-rubbing with an aqueous alcoholic solution vs traditional surgical hand-scrubbing and 30-day surgical site infection rates: a randomized equivalence study. JAMA 2002; 288: 722-7. https://doi.org/10.1001/jama.288.6.722

Nthumba PM, Stepita-Poenaru E, Poenaru D, Bird P, Allegranzi B, Pittet D, et al. Cluster-randomized, crossover trial of the efficacy of plain soap and water versus alcohol-based rub for surgical hand preparation in a rural hospital in Kenya. Br J Surg 2010; 97: 1621-8. https://doi.org/10.1002/bjs.7213

Al-Naami MY, Anjum MN, Afzal MF, Al-Yami MS, Al-Qahtani SM, Al- Dohayan AD, et al. Alcohol-based hand-rub versus traditional surgical scrub and the risk of surgical site infection: a randomized controlled equivalent trial. EWMA J. 2009; 9(3):5-10.

Marchand R, Theoret S, Dion D, Pellerin M. Clinical implementation of a scrubless chlorhexidine/ethanol pre-operative surgical hand rub. Can Oper Room Nurs J 2008; 26: 21-2, 6, 9-31.

Weight CJ, Lee MC, Palmer JS. Avagard hand antisepsis vs. traditional scrub in 3600 pediatric urologic procedures. Urology 2010; 76: 15-7. https://doi.org/10.1016/j.urology.2010.01.017

Adjoussou S, Konan Ble R, Seni K, Fanny M, Toure-Ecra A, Koffi A, et al. [Value of hand disinfection by rubbing with alcohol prior to surgery in a tropical setting]. Med Trop (Mars) 2009; 69: 463-6.

Allegranzi B, Pittet D. Role of hand hygiene in healthcare-associated infection prevention. J Hosp Infect 2009; 73: 305-315. https://doi.org/10.1016/j.jhin.2009.04.019

Rutala WA, Weber DJ. A review of single-use and reusable gowns and drapes in health care. Infect Control Hosp Epidemiol 2001; 22: 248-57. https://doi.org/10.1086/501895

Selection of surgical gowns and drapes in healthcare facilities. AAMI Technical Information Report TIR No. 11-1994; Arlington (VA); Association for the Advancement of Medical Instrumentation; 1994.

Webster J, Alghamdi A. Use of plastic adhesive drapes during surgery for preventing surgical site infection. Cochrane Database Syst Rev 2015; 2015: CD006353. https://doi.org/10.1002/14651858.CD006353.pub4

Belkin NL. Are "barrier" drapes cost effective? Today's Surg Nurse. 1998;20:18-23.

Bellchambers J, Harris JM, Cullinan P, Gaya H, Pepper JR. A prospective study of wound infection in coronary artery surgery. Eur J Cardiothorac Surg 1999; 15: 45-50. https://doi.org/10.1016/S1010-7940(98)00255-3

Castro Ferrer MJ, Masea Alvarez AM, Rodríguez García JI. Comparison of sterile, disposable surgical drapes. Enferm Clín. 2004;14:3-3. https://doi.org/10.1016/S1130-8621(04)73847-4

Treggiari M, Benevento A, Caronno R, Dionigi R. [The evaluation of the efficacy of drapes and gowns of nonwoven fabric versus drapes and gowns of cotton in reducing the incidence of postoperative wound infections]. Minerva Chir. 1992;47:49-54.

Gallagher MM, Santini L, Magliano G, Sgueglia M, Venditti F, Padula M, et al. Feasibility and safety of a simplified draping method for pacing procedures. Europace 2007; 9: 890-3. https://doi.org/10.1093/europace/eum112

Segal CG, Anderson JJ. Preoperative skin preparation of cardiac patients. AORN J 2002; 76: 821-8.

https://doi.org/10.1016/S0001-2092(06)61035-1

Al-Qahtani SM, Al-Amoudi HM, Al-Jehani S, Ashour AS, Abd-Hammad MR, Tawfik OR, et al. Post-appendectomy surgical site infection rate after using an antimicrobial film incise drape: a prospective study. Surg Infect (Larchmt) 2015; 16: 155-8.

https://doi.org/10.1089/sur.2013.188

Swenson BR, Camp TR, Mulloy DP, Sawyer RG. Antimicrobial-impregnated surgical incise drapes in the prevention of mesh infection after ventral hernia repair. Surg Infect (Larchmt) 2008; 9: 23-32. https://doi.org/10.1089/sur.2007.021

Yoshimura Y, Kubo S, Hirohashi K, Ogawa M, Morimoto K, Shirata K, et al. Plastic iodophor drape during liver surgery operative use of the iodophor- impregnated adhesive drape to prevent wound infection during high risk surgery. World J Surg 2003; 27: 685-8. https://doi.org/10.1007/s00268-003-6957-0

Chiu KY, Lau SK, Fung B, Ng KH, Chow SP. Plastic adhesive drapes and wound infection after hip fracture surgery. Aust N Z J Surg 1993; 63: 798- 801. https://doi.org/10.1111/j.1445-2197.1993.tb00343.x

Ward HR, Jennings OG, Potgieter P, Lombard CJ. Do plastic adhesive drapes prevent post caesarean wound infection? J Hosp Infect 2001; 47: 230-4. https://doi.org/10.1053/jhin.2000.0843

Tanner J, Parkinson H. Double gloving to reduce surgical cross-infection. Cochrane Database Syst Rev 2006; 2006: CD003087. https://doi.org/10.1002/14651858.CD003087.pub2

De Simone B, Sartelli M, Coccolini F, Ball CG, Brambillasca P, Chiarugi M, et al. Intraoperative surgical site infection control and prevention: a position paper and future addendum to WSES intra-abdominal infections guidelines. World J Emerg Surg 2020; 15: 10. https://doi.org/10.1186/ s13017-020-0288-4

NIHR Global Research Health Unit on Global Surgery. Routine sterile glove and instrument change at the time of abdominal wound closure to prevent surgical site infection (ChEETAh): a pragmatic, cluster-randomised trial in seven low-income and middle-income countries. Lancet 2022; 400: 1767-76.

Tulipan N, Cleves MA. Effect of an intraoperative double-gloving strategy on the incidence of cerebrospinal fluid shunt infection. J Neurosurg 2006; 104: 5-8. https://doi.org/10.3171/ped.2006.104.1.5

Dodds RD, Barker SG, Morgan NH, Donaldson DR, Thomas MH. Self protection in surgery: the use of double gloves. Br J Surg 1990; 77: 219- 20. https://doi.org/10.1002/bjs.1800770228

Atkinson MW, Owen J, Wren A, Hauth JC. The effect of manual removal of the placenta on post-cesarean endometritis. Obstet Gynecol 1996; 87: 99-102. https://doi.org/10.1016/0029-7844(95)00359-2

Cernadas M, Smulian JC, Giannina G, Ananth CV. Effects of placental delivery method and intraoperative glove changing on postcesarean febrile morbidity. J Matern Fetal Med. 1998;7(2):100-4.

https://doi.org/10.1002/(SICI)1520-6661(199803/04)7:2<100::AID-MFM9>3.0.CO;2-Q

Ventolini G, Neiger R, McKenna D. Decreasing infectious morbidity in cesarean delivery by changing gloves. J Reprod Med. 2004;49(1):13-6. https://doi.org/10.1097/00006254-200407000-00009

Ward WG, Sr., Cooper JM, Lippert D, Kablawi RO, Neiberg RH, Sherertz RJ. Glove and gown effects on intraoperative bacterial contamination. Ann Surg 2014; 259: 591-7.https://doi.org/10.1097/SLA.0b013e3182a6f2d9

Zdanowski Z, Danielsson G, Jonung T, Norgren L, Ribbe E, Thorne J, et al. Intraoperative contamination of synthetic vascular grafts. Effect of glove change before graft implantation. A prospective randomised study. Eur J Vasc Endovasc Surg 2000; 19: 283-7. https://doi.org/10.1053/ejvs.1999.1035

Sanders sR, Fortin P, Ross E, Helfet D. Outer gloves in orthopaedic procedures. Cloth compared with latex. J Bone Joint Surg Am. 1990;72(6):914-7. https://doi.org/10.2106/00004623-199072060-00019

Sebold EJ, Jordan LR. Intraoperative glove perforation. A comparative analysis. Clin Orthop Rel Res. 1993(297):242-4.

https://doi.org/10.1097/00003086-199312000-00039

Hemani ML, Lepor H. Skin preparation for the prevention of surgical site infection: which agent is best? Rev Urol 2009; 11: 190-5.

Shirahatti RG, Joshi RM, Vishwanath YK, Shinkre N, Rao S, Sankpal JS, et al. Effect of pre-operative skin preparation on post-operative wound infection. J Postgrad Med 1993; 39: 134-6.

Mishriki SF, Law DJ, Jeffery PJ. Factors affecting the incidence of postoperative wound infection. J Hosp Infect 1990; 16: 223-30. https://doi.org/10.1016/0195-6701(90)90110-A

Broach RB, Paulson EC, Scott C, Mahmoud NN. Randomized Controlled Trial of Two Alcohol-based Preparations for Surgical Site Antisepsis in Colorectal Surgery. Ann Surg 2017; 266: 946-51.https://doi.org/10.1097/SLA.0000000000002189

Cheng K, Robertson H, St Mart JP, Leanord A, McLeod I. Quantitative analysis of bacteria in forefoot surgery: a comparison of skin preparation techniques. Foot Ankle Int 2009; 30: 992-7. https://doi.org/10.3113/FAI.2009.0992

Ngai IM, Van Arsdale A, Govindappagari S, Judge NE, Neto NK, Bernstein J, et al. Skin Preparation for Prevention of Surgical Site Infection After Cesarean Delivery: A Randomized Controlled Trial. Obstet Gynecol 2015; 126: 1251-7.

https://doi.org/10.1097/AOG.0000000000001118

Saltzman MD, Nuber GW, Gryzlo SM, Marecek GS, Koh JL. Efficacy of surgical preparation solutions in shoulder surgery. J Bone Joint Surg Am 2009; 91: 1949-53. https://doi.org/10.2106/JBJS.H.00768

Savage JW, Weatherford BM, Sugrue PA, Nolden MT, Liu JC, Song JK, et al. Efficacy of surgical preparation solutions in lumbar spine surgery. J Bone Joint Surg Am 2012; 94: 490-4. https://doi.org/10.2106/JBJS.K.00471

Tuuli MG, Liu J, Stout MJ, Martin S, Cahill AG, Odibo AO, et al. A Randomized Trial Comparing Skin Antiseptic Agents at Cesarean Delivery. N Engl J Med 2016; 374: 647-55. https://doi.org/10.1056/NEJMoa1511048

Xu PZ, Fowler JR, Goitz RJ. Prospective Randomized Trial Comparing the Efficacy of Surgical Preparation Solutions in Hand Surgery. Hand (N Y) 2017; 12: 258-64. https://doi.org/10.1177/1558944716658856

Charles D, Heal CF, Delpachitra M, Wohlfahrt M, Kimber D, Sullivan J, et al. Alcoholic versus aqueous chlorhexidine for skin antisepsis: the AVALANCHE trial. CMAJ 2017; 189: E1008-E16. https://doi.org/10.1503/cmaj.161460

Gilliam D L, and Nelson C L (1990) Comparison of a one-step iodophor skin preparation versus traditional preparation in total joint surgery. Clinical orthopaedics and related research (250), 258-60.

https://doi.org/10.1097/00003086-199001000-00035

Howard R (1991) Comparison of a 10 minute aqueous iodophor and 2 minute wa terinsoluble iodophor in alcoholpreoperative skin preparation.. Complications in Surgery 10(7), 43-5.

Roberts A, Wilcox K, Devineni R, Harris R, and Osevala M (1995) Skin preparation in CA BG surgery: A prospective randomized trial. Complications in Surgery 14(6), 724,741-4, 747.

McDonnell G, Russell AD. Antiseptics and disinfectants: activity, action, and resistance. Clin Microbiol Rev 1999; 12: 147-79. https://doi.org/10.1128/CMR.12.1.147

Jalalzadeh H, Groenen H, Buis DR, Dreissen YE, Goosen JH, Ijpma FF, et al. Efficacy of different preoperative skin antiseptics on the incidence of surgical site infections: a systematic review, GRADE assessment, and network meta-analysis. Lancet Microbe 2022; 3: e762-e71. https://doi.org/10.1016/S2666-5247(22)00187-2

Hanania N.A., Zimmerman J.L. Chapter 110. Hypothermia. In: Hall J.B., Schmidt G.A., Wood L.H. Editors. Principles of Critical Care, 3e. McGraw Hill; 2005.

Diaz M, Becker DE. Thermoregulation: physiological and clinical considerations during sedation and general anesthesia. Anesth Prog 2010; 57: 25-32; quiz 3-4. https://doi.org/10.2344/0003-3006-57.1.25

Kurz A, Sessler DI, Lenhardt R. Perioperative normothermia to reduce the incidence of surgical-wound infection and shorten hospitalization. Study of Wound Infection and Temperature Group. N Engl J Med 1996; 334: 1209-15.

https://doi.org/10.1056/NEJM199605093341901

Shang A.C., Galow K.E., Essuman J.T. Utility of Perioperative Warming for the Prevention of Surgical Site Infection and Patient Rehabilitative Complications: A Systematic Review. EMJ Innov. 2020;4[1]:63-72.

https://doi.org/10.33590/emjinnov/19-00154

Melling AC, Ali B, Scott EM, Leaper DJ. Effects of preoperative warming on the incidence of wound infection after clean surgery: a randomised controlled trial. Lancet 2001; 358: 876-80. https://doi.org/10.1016/S0140-6736(01)06071-8

Frank SM, Fleisher LA, Breslow MJ, Higgins MS, Olson KF, Kelly S, et al. Perioperative maintenance of normothermia reduces the incidence of morbid cardiac events. A randomized clinical trial. JAMA 1997; 277: 1127- 34.

https://doi.org/10.1001/jama.1997.03540380041029

Rajagopalan S, Mascha E, Na J, Sessler DI. The effects of mild perioperative hypothermia on blood loss and transfusion requirement. Anesthesiology 2008; 108: 71-7. https://doi.org/10.1097/01.anes.0000296719.73450.52

Ho KM, Tan JA. Benefits and risks of maintaining normothermia during cardiopulmonary bypass in adult cardiac surgery: a systematic review. Cardiovasc Ther 2011; 29: 260-79. https://doi.org/10.1111/j.1755-5922.2009.00114.x

Whitney JD, Dellinger EP, Weber J, Swenson RE, Kent CD, Swanson PE, et al. The Effects of Local Warming on Surgical Site Infection. Surg Infect (Larchmt) 2015; 16: 595-603. https://doi.org/10.1089/sur.2013.096

High impact intervention. Care bundle to prevent surgical site infection. London; Department of Health; 2011 (http://hcai.dh.gov.uk/ files/2011/03/2011-03-14-HII-Prevent-Surgical-Site-infection-FINAL.pdf.

Gocol R, Hudziak D, Bis J, Mendrala K, Morkisz L, Podsiadlo P, et al. The Role of Deep Hypothermia in Cardiac Surgery. Int J Environ Res Public Health 2021; 18. https://doi.org/10.3390/ijerph18137061

Allen DB, Maguire JJ, Mahdavian M, Wicke C, Marcocci L, Scheuenstuhl H, et al. Wound hypoxia and acidosis limit neutrophil bacterial killing mechanisms. Arch Surg 1997; 132: 991-6. https://doi.org/10.1001/archsurg.1997.01430330057009

Kurz A, Sessler DI, Lenhardt R. Perioperative Normothermia to Reduce the Incidence of Surgical-Wound Infection and Shorten Hospitalization. New England Journal of Medicine 1996; 334: 1209-16.

https://doi.org/10.1056/NEJM199605093341901

Greif R, Akça O, Horn EP, Kurz A, Sessler DI. Supplemental perioperative oxygen to reduce the incidence of surgical-wound infection. N Engl J Med 2000; 342: 161-7. https://doi.org/10.1056/NEJM200001203420303

Global Guidelines for the Prevention of Surgical Site Infection. WHO Guidelines Approved by the Guidelines Review Committee. Geneva. 2018.

de Jonge S, Egger M, Latif A, Loke YK, Berenholtz S, Boermeester M, et al. Effectiveness of 80% vs 30-35% fraction of inspired oxygen in patients undergoing surgery: an updated systematic review and meta-analysis. Br J Anaesth 2019; 122: 325-34. https://doi.org/10.1016/j.bja.2018.11.024

Mattishent K, Thavarajah M, Sinha A, Peel A, Egger M, Solomkin J, et al. Safety of 80% vs 30-35% fraction of inspired oxygen in patients undergoing surgery: a systematic review and meta-analysis. Br J Anaesth 2019; 122: 311-24.

https://doi.org/10.1016/j.bja.2018.11.026

Kabon B, Akça O, Taguchi A, Nagele A, Jebadurai R, Arkilic CF, et al. Supplemental intravenous crystalloid administration does not reduce the risk of surgical wound infection. Anesth Analg 2005; 101: 1546-53.

https://doi.org/10.1213/01.ANE.0000180217.57952.FE

Voldby AW, Brandstrup B. Fluid therapy in the perioperative setting-a clinical review. J Intensive Care 2016; 4: 27. https://doi.org/10.1186/ s40560-016-0154-3

Wenkui Y, Ning L, Jianfeng G, Weiqin L, Shaoqiu T, Zhihui T, et al. Restricted peri-operative fluid administration adjusted by serum lactate level improved outcome after major elective surgery for gastrointestinal malignancy. Surgery 2010; 147: 542-52. https://doi.org/10.1016/j.surg.2009.10.036

Wilson J, Woods I, Fawcett J, Whall R, Dibb W, Morris C, et al. Reducing the risk of major elective surgery: randomised controlled trial of preoperative optimisation of oxygen delivery. Bmj 1999; 318: 1099-103.

https://doi.org/10.1136/bmj.318.7191.1099

Forget P, Lois F, de Kock M. Goal-directed fluid management based on the pulse oximeter-derived pleth variability index reduces lactate levels and improves fluid management. Anesth Analg 2010; 111: 910-4.

https://doi.org/10.1213/ANE.0b013e3181eb624f

Harten J, Crozier JE, McCreath B, Hay A, McMillan DC, McArdle CS, et al. Effect of intraoperative fluid optimisation on renal function in patients undergoing emergency abdominal surgery: a randomised controlled pilot study (ISRCTN 11799696). Int J Surg 2008; 6: 197-204. https://doi.org/10.1016/j.ijsu.2008.03.002

Mythen MG, Webb AR. Perioperative plasma volume expansion reduces the incidence of gut mucosal hypoperfusion during cardiac surgery. Arch Surg 1995; 130: 423-9. https://doi.org/10.1001/archsurg.1995.01430040085019

Pillai P, McEleavy I, Gaughan M, Snowden C, Nesbitt I, Durkan G, et al. A double-blind randomized controlled clinical trial to assess the effect of Doppler optimized intraoperative fluid management on outcome following radical cystectomy. J Urol 2011; 186: 2201-6. https://doi.org/10.1016/j.juro.2011.07.093

Scheeren TW, Wiesenack C, Gerlach H, Marx G. Goal-directed intraoperative fluid therapy guided by stroke volume and its variation in high-risk surgical patients: a prospective randomized multicentre study. J Clin Monit Comput 2013; 27: 225-33. https://doi.org/10.1007/s10877-013-9461-6

Smetkin AA, Kirov MY, Kuzkov VV, Lenkin AI, Eremeev AV, Slastilin VY, et al. Single transpulmonary thermodilution and continuous monitoring of central venous oxygen saturation during off-pump coronary surgery. Acta Anaesthesiol Scand 2009; 53: 505-14. https://doi.org/10.1111/j.1399-6576.2008.01855.x

Venn R, Steele A, Richardson P, Poloniecki J, Grounds M, Newman P. Randomized controlled trial to investigate influence of the fluid challenge on duration of hospital stay and perioperative morbidity in patients with hip fractures. Br J Anaesth 2002; 88: 65-71. https://doi.org/10.1093/bja/88.1.65

Wakeling HG, McFall MR, Jenkins CS, Woods WG, Miles WF, Barclay GR, et al. Intraoperative oesophageal Doppler guided fluid management shortens postoperative hospital stay after major bowel surgery. Br J Anaesth 2005; 95: 634-42.

https://doi.org/10.1093/bja/aei223

Benes J, Chytra I, Altmann P, Hluchy M, Kasal E, Svitak R, et al. Intraoperative fluid optimization using stroke volume variation in high risk surgical patients: results of prospective randomized study. Critical Care 2010; 14: R118.

https://doi.org/10.1186/cc9070

Lopes MR, Oliveira MA, Pereira VO, Lemos IP, Auler JO, Jr., Michard F. Goal-directed fluid management based on pulse pressure variation monitoring during high-risk surgery: a pilot randomized controlled trial. Crit Care 2007; 11: R100.

https://doi.org/10.1186/cc6117

Brandstrup B, Tonnesen H, Beier-Holgersen R, Hjortso E, Ording H, Lindorff-Larsen K, et al. Effects of intravenous fluid restriction on postoperative complications: comparison of two perioperative fluid regimens: a randomized assessor-blinded multicenter trial. Ann Surg 2003; 238: 641-8. https://doi.org/10.1097/01.sla.0000094387.50865.23

Holte K, Foss NB, Andersen J, Valentiner L, Lund C, Bie P, et al. Liberal or restrictive fluid administration in fast-track colonic surgery: a randomized, double-blind study†. BJA: British Journal of Anaesthesia 2007; 99: 500-8.

https://doi.org/10.1093/bja/aem211

Lobo DN, Bostock KA, Neal KR, Perkins AC, Rowlands BJ, Allison SP. Effect of salt and water balance on recovery of gastrointestinal function after elective colonic resection: a randomised controlled trial. Lancet 2002; 359: 1812-8.

https://doi.org/10.1016/S0140-6736(02)08711-1

Nisanevich V, Felsenstein I, Almogy G, Weissman C, Einav S, Matot I. Effect of intraoperative fluid management on outcome after intraabdominal surgery. Anesthesiology 2005; 103: 25-32.

https://doi.org/10.1097/00000542-200507000-00008

McKendry M, McGloin H, Saberi D, Caudwell L, Brady AR, Singer M. Randomised controlled trial assessing the impact of a nurse delivered, flow monitored protocol for optimisation of circulatory status after cardiac surgery. Bmj 2004; 329: 258.

https://doi.org/10.1136/bmj.38156.767118.7C

Pearse R, Dawson D, Fawcett J, Rhodes A, Grounds RM, Bennett ED. Early goal-directed therapy after major surgery reduces complications and duration of hospital stay. A randomised, controlled trial [ISRCTN38797445]. Crit Care 2005; 9: R687-93.

Voldby AW, Brandstrup B. Fluid therapy in the perioperative setting-a clinical review. Journal of Intensive Care 2016; 4: 27. https://doi.org/10.1186/s40560-016-0154-3

Raghunathan K, Shaw A. Hydroxyethyl starch or saline in intensive care. N Engl J Med 2013; 368: 774-5.

https://doi.org/10.1056/NEJMc1215977

Joosten A, Delaporte A, Ickx B, Touihri K, Stany I, Barvais L, et al. Crystalloid versus Colloid for Intraoperative Goal-directed Fluid Therapy Using a Closed-loop System: A Randomized, Double-blinded, Controlled Trial in Major Abdominal Surgery. Anesthesiology 2018; 128: 55-66. https://doi.org/10.1097/ALN.0000000000001936

Van Der Linden P, James M, Mythen M, Weiskopf RB. Safety of modern starches used during surgery. Anesth Analg 2013; 116: 35-48. https://doi.org/10.1213/ANE.0b013e31827175da

Semler MW, Kellum JA. Balanced Crystalloid Solutions. Am J Respir Crit Care Med 2019; 199: 952-60.

https://doi.org/10.1164/rccm.201809-1677CI

Awad S, Allison SP, Lobo DN. The history of 0.9% saline. Clin Nutr 2008; 27: 179-88.

https://doi.org/10.1016/j.clnu.2008.01.008

Surgical site infection: evidence update (April 2019). London: National Institute for Health and Care Excellence (NICE); 2019.

Zhang J, Qiao H, He Z, Wang Y, Che X, Liang W. Intraoperative fluid management in open gastrointestinal surgery: goal-directed versus restrictive. Clinics (Sao Paulo) 2012; 67: 1149-55. https://doi.org/10.6061/clinics/2012(10)06

Feldheiser A, Pavlova V, Bonomo T, Jones A, Fotopoulou C, Sehouli J, et al. Balanced crystalloid compared with balanced colloid solution using a goal-directed haemodynamic algorithm. BJA: British Journal of Anaesthesia 2012; 110: 231-40.

https://doi.org/10.1093/bja/aes377

Yates DR, Davies SJ, Milner HE, Wilson RJ. Crystalloid or colloid for goal- directed fluid therapy in colorectal surgery. Br J Anaesth 2014; 112: 281-9. https://doi.org/10.1093/bja/aet307

Moretti EW, Robertson KM, El-Moalem H, Gan TJ. Intraoperative colloid administration reduces postoperative nausea and vomiting and improves postoperative outcomes compared with crystalloid administration. Anesth Analg 2003; 96: 611-7.

https://doi.org/10.1213/00000539-200302000-00056

Werner J, Hunsicker O, Schneider A, Stein H, von Heymann C, Freitag A, et al. Balanced 10% hydroxyethyl starch compared with balanced 6% hydroxyethyl starch and balanced crystalloid using a goal-directed hemodynamic algorithm in pancreatic surgery: A randomized clinical trial. Medicine (Baltimore) 2018; 97: e0579.

https://doi.org/10.1097/MD.0000000000010579

Shah RB, Shah VR, Butala BP, Parikh GP. Effect of intraoperative human albumin on early graft function in renal transplantation. Saudi J Kidney Dis Transpl 2014; 25: 1148-53. https://doi.org/10.4103/1319-2442.144246

Abdallah E, El-Shishtawy S, Mosbah O, Zeidan M. Comparison between the effects of intraoperative human albumin and normal saline on early graft function in renal transplantation. Int Urol Nephrol 2014; 46: 2221-6.

https://doi.org/10.1007/s11255-014-0785-z

Jafar N, Edriss H, Nugent K. The Effect of Short-Term Hyperglycemia on the Innate Immune System. Am J Med Sci 2016; 351: 201-11. https://doi.org/10.1016/j.amjms.2015.11.011

Berbudi A, Rahmadika N, Tjahjadi AI, Ruslami R. Type 2 Diabetes and its Impact on the Immune System. Curr Diabetes Rev 2020; 16: 442-9. https://doi.org/10.2174/1573399815666191024085838

Li X, Weber NC, Cohn DM, Hollmann MW, DeVries JH, Hermanides J, et al. Effects of Hyperglycemia and Diabetes Mellitus on Coagulation and Hemostasis. J Clin Med 2021; 10. https://doi.org/10.3390/jcm10112419

Duncan AE. perioperative glucose Hyperglycemia and management. Curr Pharm Des 2012; 18: 6195-203.

https://doi.org/10.2174/138161212803832236

Abdelmalak BB, Bonilla A, Mascha EJ, Maheshwari A, Tang WH, You J, et al. Dexamethasone, light anaesthesia, and tight glucose control (DeLiT) randomized controlled trial. Br J Anaesth 2013; 111: 209-21. https://doi.org/10.1093/bja/aet050

Albacker TB, Carvalho G, Schricker T, Lachapelle K. Myocardial protection during elective coronary artery bypass grafting using high-dose insulin therapy. Ann Thorac Surg 2007; 84: 1920-7; discussion -7.

https://doi.org/10.1016/j.athoracsur.2007.07.001

Azarfarin R, Sheikhzadeh D, Mirinazhad M, Bilehjani E, Alizadehasl A. Do nondiabetic patients undergoing coronary artery bypass grafting surgery require intraoperative management of hyperglycemia? Acta Anaesthesiol Taiwan 2011; 49: 41-5.

https://doi.org/10.1016/j.aat.2011.05.009

Cao S, Zhou Y, Chen D, Niu Z, Wang D, Lv L, et al. Intensive versus conventional insulin therapy in nondiabetic patients receiving parenteral nutrition after D2 gastrectomy for gastric cancer: a randomized controlled trial. J Gastrointest Surg 2011; 15: 1961-8.https://doi.org/10.1007/s11605-011-1654-z

Chan RP, Galas FR, Hajjar LA, Bello CN, Piccioni MA, Auler JO, Jr. Intensive perioperative glucose control does not improve outcomes of patients submitted to open-heart surgery: a randomized controlled trial. Clinics (Sao Paulo) 2009; 64: 51-60. https://doi.org/10.1590/S1807-59322009000100010

Duncan AE, Sessler DI, Sato H, Sato T, Nakazawa K, Carvalho G, et al. Hyperinsulinemic Normoglycemia during Cardiac Surgery Reduces a Composite of 30-day Mortality and Serious In-hospital Complications: A Randomized Clinical Trial. Anesthesiology 2018; 128: 1125-39. https://doi.org/10.1097/ALN.0000000000002156

Emam IA, Allan A, Eskander K, Dhanraj K, Farag el S, El-Kadi Y, et al. Our experience of controlling diabetes in the peri-operative period of patients who underwent cardiac surgery. Diabetes Res Clin Pract 2010; 88: 242-6.

https://doi.org/10.1016/j.diabres.2010.03.002

Ji Q, Ding W, Mei Y, Wang X, Feng J, Cai J. Protective effects of tight glucose control during cardiopulmonary bypass on myocardium in adult nondiabetic patients undergoing valve replacement. Can J Cardiol 2014; 30: 1429-35.

https://doi.org/10.1016/j.cjca.2014.05.020

Rujirojindakul P, Liabsuetrakul T, McNeil E, Chanchayanon T, Wasinwong W, Oofuvong M, et al. Safety and efficacy of intensive intraoperative glycaemic control in cardiopulmonary bypass surgery: a randomised trial. Acta Anaesthesiol Scand 2014; 58: 588-96. https://doi.org/10.1111/aas.12305

Giakoumidakis K, Eltheni R, Patelarou E, Theologou S, Patris V, Michopanou N, et al. Effects of intensive glycemic control on outcomes of cardiac surgery. Heart Lung 2013; 42: 146-51. https://doi.org/10.1016/j.hrtlng.2012.12.007

Schricker T, Sato H, Beaudry T, Codere T, Hatzakorzian R, Pruessner JC. Intraoperative maintenance of normoglycemia with insulin and glucose preserves verbal learning after cardiac surgery. PLoS One 2014; 9: e99661.

https://doi.org/10.1371/journal.pone.0099661

Smith A, Grattan A, Harper M, Royston D, Riedel BJ. Coronary revascularization: a procedure in transition from on-pumpto off-pump? The role of glucose-insulin-potassium revisited in a randomized, placebo- controlled study. J Cardiothorac Vasc Anesth 2002; 16: 413-20. https://doi.org/10.1053/jcan.2002.125151

Tohya A, Kohjitani A, Ohno S, Yamashita K, Manabe Y, Sugimura M. Effects of glucose-insulin infusion during major oral and maxillofacial surgery on postoperative complications and outcomes. JA Clin Rep 2018; 4: 9.

https://doi.org/10.1186/s40981-018-0148-3

Zheng R, Gu C, Wang Y, Yang Z, Dou K, Wang J, et al. Impacts of intensive insulin therapy in patients undergoing heart valve replacement. Heart Surg Forum 2010; 13: E292-8. https://doi.org/10.1532/HSF98.20101017

Desai SP, Henry LL, Holmes SD, Hunt SL, Martin CT, Hebsur S, et al. Strict versus liberal target range for perioperative glucose in patients undergoing coronary artery bypass grafting: a prospective randomized controlled trial. J Thorac Cardiovasc Surg 2012; 143: 318-25. https://doi.org/10.1016/j.jtcvs.2011.10.070

Gandhi GY, Nuttall GA, Abel MD, Mullany CJ, Schaff HV, O'Brien PC, et al. Intensive intraoperative insulin therapy versus conventional glucose management during cardiac surgery: a randomized trial. Ann Intern Med 2007; 146: 233-43.

https://doi.org/10.7326/0003-4819-146-4-200702200-00002

Yuan J, Liu T, Zhang X, Si Y, Ye Y, Zhao C, et al. Intensive Versus Conventional Glycemic Control in Patients with Diabetes During Enteral Nutrition After Gastrectomy. J Gastrointest Surg 2015; 19: 1553-8.

https://doi.org/10.1007/s11605-015-2871-7

Butterworth J, Wagenknecht LE, Legault C, Zaccaro DJ, Kon ND, Hammon JW, Jr., et al. Attempted control of hyperglycemia during cardiopulmonary bypass fails to improve neurologic or neurobehavioral outcomes in patients without diabetes mellitus undergoing coronary artery bypass grafting. J Thorac Cardiovasc Surg 2005; 130: 1319.

https://doi.org/10.1016/j.jtcvs.2005.02.049

Chaney MA, Nikolov MP, Blakeman BP, Bakhos M. Attempting to Maintain Normoglycemia During Cardiopulmonary Bypass with Insulin May Initiate Postoperative Hypoglycemia. Anesthesia & Analgesia 1999; 89: 1091-5.

https://doi.org/10.1213/00000539-199911000-00004

Okabayashi T, Nishimori I, Yamashita K, Sugimoto T, Maeda H, Yatabe T, et al. Continuous postoperative blood glucose monitoring and control by artificial pancreas in patients having pancreatic resection: a prospective randomized clinical trial. Arch Surg 2009; 144: 933-7. https://doi.org/10.1001/archsurg.2009.176

Groban L, Butterworth J, Legault C, Rogers AT, Kon ND, Hammon JW. Intraoperative insulin therapy does not reduce the need for inotropic or antiarrhythmic therapy after cardiopulmonary bypass. J Cardiothorac Vasc Anesth 2002; 16: 405-12.

https://doi.org/10.1053/jcan.2002.125152

Grey nosocomial Perdrizet Reduction of GA. NJ, infections in the surgical intensive-care unit by strict glycemic control. Endocr Pract 2004; 10 Suppl 2: 46-52. https://doi.org/10.4158/EP.10.S2.46

Ingels C, Debaveye Y, Milants I, Buelens E, Peeraer A, Devriendt Y, et al. Strict blood glucose control with insulin during intensive care after cardiac surgery: impact on 4-years survival, dependency on medical care, and quality-of-life. Eur Heart J 2006; 27: 2716-24. https://doi.org/10.1093/eurheartj/ehi855

Szabó Z, Arnqvist H, Håkanson E, Jorfeldt L, Svedjeholm R. Effects of high-dose glucose-insulin-potassium on myocardial metabolism after coronary surgery in patients with Type II diabetes. Clin Sci (Lond) 2001; 101: 37-43.

https://doi.org/10.1042/cs1010037

Visser L, Zuurbier CJ, Hoek FJ, Opmeer BC, de Jonge E, de Mol BA, et al. Glucose, insulin and potassium applied as perioperative hyperinsulinaemic normoglycaemic clamp: effects on inflammatory response during coronary artery surgery. Br J Anaesth 2005; 95: 448-57. https://doi.org/10.1093/bja/aei220

Hoedemaekers CW, Pickkers P, Netea MG, van Deuren M, Van der Hoeven JG. Intensive insulin therapy does not alter the inflammatory response in patients undergoing coronary artery bypass grafting: a randomized controlled trial [ISRCTN95608630]. Crit Care 2005; 9: R790-7. https://doi.org/10.1186/cc3911

Sato H, Lattermann R, Carvalho G, Sato T, Metrakos P, Hassanain M, et al. Perioperative glucose and insulin administration while maintaining normoglycemia (GIN therapy) in patients undergoing major liver resection. Anesth Analg 2010; 110: 1711-8. https://doi.org/10.1213/ANE.0b013e3181d90087

Whiteside OJ, Tytherleigh MG, Thrush S, Farouk R, Galland RB. Intra- operative peritoneal lavage--who does it and why? Ann R Coll Surg Engl 2005; 87: 255-8. https://doi.org/10.1308/1478708051847

Diana M, Hübner M, Eisenring MC, Zanetti G, Troillet N, Demartines N. Measures to prevent surgical site infections: what surgeons (should) do. World J Surg 2011; 35: 280-8.https://doi.org/10.1007/s00268-010-0862-0

Pivot D, Tiv M, Luu M, Astruc K, Aho S, Fournel I. Survey of intraoperative povidone-iodine application to prevent surgical site infection in a French region. J Hosp Infect 2011; 77: 363-4. https://doi.org/10.1016/j.jhin.2010.11.016

Chen PJ, Hua YM, Toh HS, Lee MC. Topical antibiotic prophylaxis for surgical wound infections in clean and clean-contaminated surgery: a systematic review and meta-analysis. BJS Open 2021; 5. https://doi.org/10.1093/bjsopen/zrab125

Norman G, Atkinson RA, Smith TA, Rowlands C, Rithalia AD, Crosbie EJ, et al. Intracavity lavage and wound irrigation for prevention of surgical site infection. Cochrane Database Syst Rev 2017; 10: Cd012234.

https://doi.org/10.1002/14651858.CD012234.pub2

Hinarejos P, Guirro P, Leal J, Montserrat F, Pelfort X, Sorli ML, et al. The use of erythromycin and colistin-loaded cement in total knee arthroplasty does not reduce the incidence of infection: a prospective randomized study in 3000 knees. J Bone Joint Surg Am 2013; 95: 769-74. https://doi.org/10.2106/JBJS.L.00901

Tubaki VR, Rajasekaran S, Shetty AP. Effects of using intravenous antibiotic only versus local intrawound vancomycin antibiotic powder application in addition to intravenous antibiotics on postoperative infection in spine surgery in 907 patients. Spine (Phila Pa 1976) 2013; 38: 2149-55. https://doi.org/10.1097/BRS.0000000000000015

Rickett JW, Jackson BT. Topical ampicillin in the appendicectomy wound: report of double-blind trial. Br Med J 1969; 4: 206-7. https://doi.org/10.1136/bmj.4.5677.206

Moesgaard F, Nielsen ML, Hjortrup A, Kjersgaard P, Sørensen C, Larsen PN, et al. Intraincisional antibiotic in addition to systemic antibiotic treatment fails to reduce wound infection rates in contaminated abdominal surgery. A controlled clinical trial. Dis Colon Rectum 1989; 32: 36-8. https://doi.org/10.1007/BF02554723

Evans C, Pollock AV, Rosenberg IL. The reduction of surgical wound infections by topical cephaloridine: A controlled clinical trial. British Journal of Surgery 2005; 61: 133-5. https://doi.org/10.1002/bjs.1800610215

Gray JG, Lee MJ. The effect of topical povidone iodine on wound infection following abdominal surgery. Br J Surg 1981; 68: 310-3. https://doi.org/10.1002/bjs.1800680506

Walsh JA, Watts JM, McDonald PJ, Finlay-Jones JJ. The effect of topical povidone-iodine on the incidence of infection in surgical wounds. Br J Surg 1981; 68: 185-9. https://doi.org/10.1002/bjs.1800680315

Harihara Y, Konishi T, Kobayashi H, Furushima K, Ito K, Noie T, et al. Effects of applying povidone-iodine just before skin closure. Dermatology 2006; 212 Suppl 1: 53-7. https://doi.org/10.1159/000089200

Cordtz T, Schouenborg L, Laursen K, Daugaard HO, Buur K, Munk Christensen B, et al. The effect of incisional plastic drapes and redisinfection of operation site on wound infection following caesarean section. J Hosp Infect 1989; 13: 267-72.

https://doi.org/10.1016/0195-6701(89)90007-8

Collin A, Gustafsson UM, Smedh K, Pahlman L, Graf W, Folkesson J. Effect of local gentamicin-collagen on perineal wound complications and cancer recurrence after abdominoperineal resection: a multicentre randomized controlled trial. Colorectal Dis 2013; 15: 341-6. https://doi.org/10.1111/j.1463-1318.2012.03196.x

Migaczewski M, Zub-Pokrowiecka A, Budzynski P, Matlok M, Budzynski A. Prevention of early infective complications after laparoscopic splenectomy with the Garamycin sponge. Wideochir Inne Tech Maloinwazyjne 2012; 7: 105-10.

https://doi.org/10.5114/wiitm.2011.27151

Nowacki MP, Rutkowski A, Oledzki J, Chwalinski M. Prospective, randomized trial examining the role of gentamycin-containing collagen sponge in the reduction of postoperative morbidity in rectal cancer patients: early results and surprising outcome at 3 year follow up. Int J Colorectal Dis 2005; 20: 114-20.

https://doi.org/10.1007/s00384-004-0632-2

Westberg M, Frihagen F, Brun OC, Figved W, Grcgaard B, Valland H, et al. Effectiveness of gentamicin containing collagen sponges for prevention of surgical site infection after hip arthroplasty: a multicenter randomized trial. Clin Infect Dis 2015; 60: 1752-9. https://doi.org/10.1093/cid/civ162

Haase O, Raue W, Bohm B, Neuss H, Scharfenberg M, Schwenk W. Subcutaneous gentamycin implant to reduce wound infections after loop ileostomy closure: a randomized, double blind, placebo-controlled trial. Dis Colon Rectum 2005; 48: 2025-31. https://doi.org/10.1007/s10350-005-0164-z

Schimmer C, Ozkur M, Sinha B, Hain J, Gorski A, Hager B, et al. Gentamicin collagen sponge reduces sternal wound complications after heart surgery: a controlled, prospectively randomized, double blind study. J Thorac Cardiovasc Surg 2012; 143: 194-200. https://doi.org/10.1016/j.jtcvs.2011.05.035

Mingeot-Leclercq MP, Tulkens PM. Aminoglycosides: nephrotoxicity. Antimicrob Agents Chemother 1999; 43: 1003-12.

https://doi.org/10.1128/AAC.43.5.1003

Mueller TC, Loos M, Haller B, Mihaljevic AL, Nitsche U, Wilhelm D, et al. Intra-operative wound irrigation to reduce surgical site infections after abdominal surgery: a systematic review and meta-analysis. Langenbecks Arch Surg 2015; 400: 167-81. https://doi.org/10.1007/s00423-015-1279-x

de Jonge SW, Boldingh QJJ, Solomkin JS, Allegranzi B, Egger M, Dellinger EP, et al. Systematic Review and Meta Analysis of Randomized Controlled Trials Evaluating Prophylactic Intra Operative Wound Irrigation for the Prevention of Surgical Site Infections. Surg Infect (Larchmt) 2017; 18: 508- 19. https://doi.org/10.1089/sur.2016.272

Al-Ramahi M, Bata M, Sumreen I, Amr M. Saline irrigation and wound infection in abdominal gynecologic surgery. Int J Gynaecol Obstet 2006; 94: 33-6. https://doi.org/10.1016/j.ijgo.2006.03.030

Baker DM, Jones JA, Nguyen-Van-Tam JS, Lloyd JH, Morris DL, Bourke JB, et al. Taurolidine peritoneal lavage as prophylaxis against infection after elective colorectal surgery. Br J Surg 1994; 81: 1054-6.

https://doi.org/10.1002/bjs.1800810743

Freischlag J, McGrattan M, Busuttil RW. Topical versus systemic cephalosporin administration in elective biliary operations. Surgery 1984; 96: 686-93.

Ruiz-Tovar J, Llavero C, Gamallo C, Santos J, Calpena R, Arroyo A, et al. Effect of Peritoneal Lavage with Clindamycin-Gentamicin Solution during Elective Colorectal Cancer Surgery on the Oncologic Outcome. Surg Infect (Larchmt) 2016; 17: 65-70. https://doi.org/10.1089/sur.2015.064

Silverman SH, Ambrose NS, Youngs DJ, Shepherd AF, Roberts AP, Keighley MR. The effect of peritoneal lavage with tetracycline solution on postoperative infection. A prospective, randomized, clinical trial. Dis Colon Rectum 1986; 29: 165-9.

https://doi.org/10.1007/BF02555014

Cervantes-Sánchez CR, Gutiérrez-Vega R, Vázquez-Carpizo JA, Clark P, Athié-Gutiérrez C. Syringe pressure irrigation of subdermic tissue after appendectomy to decrease the incidence of postoperative wound infection. World J Surg 2000; 24: 38-41; discussion -2. https://doi.org/10.1007/s002689910008

Hargrove R, Ridgeway S, Russell R, Norris M, Packham I, Levy B. Does pulse lavage reduce hip hemiarthroplasty infection rates? J Hosp Infect 2006; 62: 446-9. https://doi.org/10.1016/j.jhin.2005.07.012

Nikfarjam M, Weinberg L, Fink MA, Muralidharan V, Starkey G, Jones R, et al. Pressurized pulse irrigation with saline reduces surgical-site infections following major hepatobiliary and pancreatic surgery: randomized controlled trial. World J Surg 2014; 38: 447-55. https://doi.org/10.1007/s00268-013-2309-x

Chang FY, Chang MC, Wang ST, Yu WK, Liu CL, Chen TH. Can povidone- iodine solution be used safely in a spinal surgery? Eur Spine J 2006; 15: 1005-14. https://doi.org/10.1007/s00586-005-0975-6

Cheng MT, Chang MC, Wang ST, Yu WK, Liu CL, Chen TH. Efficacy of dilute betadine solution irrigation in the prevention of postoperative infection of spinal surgery. Spine (Phila Pa 1976) 2005; 30: 1689-93.

https://doi.org/10.1097/01.brs.0000171907.60775.85

Kokavec M, Fristáková M. [Efficacy of antiseptics in the prevention of post-operative infections of the proximal femur, hip and pelvis regions in orthopedic pediatric patients. Analysis of the first results]. Acta Chir Orthop Traumatol Cech 2008; 75: 106-9. https://doi.org/10.55095/achot2008/018

Lau WY, Fan ST, Chu KW, Yip WC, Chong KK, Wong KK. Combined topical povidone-iodine and systemic antibiotics in postappendicectomy wound sepsis. Br J Surg 1986; 73: 958-60. https://doi.org/10.1002/bjs.1800731205

Rogers DM, Blouin GS, O'Leary JP. Povidone-iodine wound irrigation and wound sepsis. Surg Gynecol Obstet 1983; 157: 426-30.

Sindelar WF, Mason GR. Intraperitoneal irrigation with povidone-iodine solution for the prevention of intra-abdominal abscesses in the bacterially contaminated abdomen. Surg Gynecol Obstet 1979; 148: 409-11.

Sindelar WF, Brower ST, Merkel AB, Takesue EI. Randomised trial of intraperitoneal irrigation with low molecular weight povidone-iodine solution to reduce intra abdominal infectious complications. J Hosp Infect 1985; 6 Suppl A: 103-14.

https://doi.org/10.1016/S0195-6701(85)80054-2

Juul P, Merrild U, Kronborg O. Topical ampicillin in addition to a systemic antibiotic prophylaxis in elective colorectal surgery. A prospective randomized study. Dis Colon Rectum 1985; 28: 804-6. https://doi.org/10.1007/BF02555480

Pitt HA, Postier RG, MacGowan AW, Frank LW, Surmak AJ, Sitzman JV, et al. Prophylactic antibiotics in vascular surgery. Topical, systemic, or both? Ann Surg 1980; 192: 356-64. https://doi.org/10.1097/00000658-198009000-00011

Ko W, Lazenby WD, Zelano JA, Isom OW, Krieger KH. Effects of shaving methods and intraoperative irrigation on suppurative mediastinitis after bypass operations. Ann Thorac Surg 1992; 53: 301-5.

https://doi.org/10.1016/0003-4975(92)91337-9

Liza GO. Surgical Wound Closure and Healing. En: Prof. Ana Colette M, Dr. Rui Damásio A, Prof. Muzeyyen G, editors. Wound Healing - Recent Advances and Future Opportunities. Rijeka: IntechOpen; 2022. p. Ch. 6.

Mahesh L, Kumar VR, Jain A, Shukla S, Aragoneses JM, Martínez González JM, et al. Bacterial Adherence Around Sutures of Different Material at Grafted Site: A Microbiological Analysis. Materials (Basel) 2019; 12.

https://doi.org/10.3390/ma12182848

Tacconi L, Spinelli R, Signorelli F. Skin Glue for Wounds Closure in Brain Surgery: Our Updated Experience. World Neurosurg 2019; 121: e940-e6. https://doi.org/10.1016/j.wneu.2018.10.023

Mostofi K, Peyravi M, Shirbacheh A, Shirbache K. A comparison between different suture techniques in lumbar spine surgery. Int Wound J 2023; 20: 296-301. https://doi.org/10.1111/iwj.13875

Fayyaz GQ, Gill NA, Alam I, Chaudary A, Aslam M, Ishaaq I, et al. Continuous Versus Interrupted Sutures for Primary Cleft Palate Repair. Plast Reconstr Surg Glob Open 2018; 6: e2001. https://doi.org/10.1097/GOX.0000000000002001

Byrne M, Aly A. The Surgical Suture. Aesthet Surg J 2019; 39: S67-S72. https://doi.org/10.1093/asj/sjz036

Seim BE, Tonnessen T, Woldbaek PR. Triclosan-coated sutures do not reduce leg wound infections after coronary artery bypass grafting. Interact Cardiovasc Thorac Surg 2012; 15: 411-5. https://doi.org/10.1093/icvts/ivs266

Isik I, Selimen D, Senay S, Alhan C. Efficiency of antibacterial suture material in cardiac surgery: a double-blind randomized prospective study. Heart Surg Forum 2012; 15: E40-5. https://doi.org/10.1532/HSF98.20111106

Turtiainen J, Saimanen EI, Makinen KT, Nykanen AI, Venermo MA, Uurto IT, et al. Effect of triclosan-coated sutures on the incidence of surgical wound infection after lower limb revascularization surgery: a randomized controlled trial. World J Surg 2012; 36: 2528-34. https://doi.org/10.1007/s00268-012-1717-7

Baracs J, Huszár O, Sajjadi SG, Horváth OP. Surgical site infections after abdominal closure in colorectal surgery using triclosan-coated absorbable suture (PDS Plus) vs. uncoated sutures (PDS II): a randomized multicenter study. Surg Infect (Larchmt) 2011; 12: 483-9. https://doi.org/10.1089/sur.2011.001

Diener MK, Knebel P, Kieser M, Schuler P, Schiergens TS, Atanassov V, et al. Effectiveness of triclosan-coated PDS Plus versus uncoated PDS II sutures for prevention of surgical site infection after abdominal wall closure: the randomised controlled PROUD trial. Lancet 2014; 384: 142-52. https://doi.org/10.1016/S0140-6736(14)60238-5

Ichida K, Noda H, Kikugawa R, Hasegawa F, Obitsu T, Ishioka D, et al. Effect of triclosan-coated sutures on the incidence of surgical site infection after abdominal wall closure in gastroenterological surgery: a double-blind, randomized controlled trial in a single center. Surgery 2018. https://doi.org/10.1016/j.surg.2017.12.020

Justinger C, Slotta JE, Ningel S, Graber S, Kollmar O, Schilling MK. Surgical- site infection after abdominal wall closure with triclosan-impregnated polydioxanone sutures: results of a randomized clinical pathway facilitated trial (NCT00998907). Surgery 2013; 154: 589-95. https://doi.org/10.1016/j.surg.2013.04.011

Mattavelli I, Rebora P, Doglietto G, Dionigi P, Dominioni L, Luperto M, et al. Multi-Center Randomized Controlled Trial on the Effect of Triclosan-Coated Sutures on Surgical Site Infection after Colorectal Surgery. Surg Infect (Larchmt) 2015; 16: 226-35. https://doi.org/10.1089/sur.2014.005

Nakamura T, Kashimura N, Noji T, Suzuki O, Ambo Y, Nakamura F, et al. Triclosan-coated sutures reduce the incidence of wound infections and the costs after colorectal surgery: a randomized controlled trial. Surgery 2013; 153: 576-83.

https://doi.org/10.1016/j.surg.2012.11.018

Galal I, El-Hindawy K. Impact of using triclosan-antibacterial sutures on incidence of surgical site infection. Am J Surg 2011; 202: 133-8. https://doi.org/10.1016/j.amjsurg.2010.06.011

Renko M, Paalanne N, Tapiainen T, Hinkkainen M, Pokka T, Kinnula S, et al. Triclosan-containing sutures versus ordinary sutures for reducing surgical site infections in children: a double-blind, randomised controlled trial. Lancet Infect Dis 2017; 17: 50-7. https://doi.org/10.1016/S1473-3099(16)30373-5

Leaper DJ, Benson CE. Subcuticular skin closure after inguinal surgery. A controlled trial of polypropylene or polydioxanone. J R Coll Surg Edinb 1985; 30: 234-6.

Orr JW, Jr., Montz FJ, Barter J, Schaitzberg SD, Delmore JE, Dodson MK, et al. Continuous abdominal fascial closure: a randomized controlled trial of poly(L-lactide/glycolide). Gynecol Oncol 2003; 90: 342-7.

https://doi.org/10.1016/S0090-8258(03)00267-1

Gililland JM, Anderson LA, Barney JK, Ross HL, Pelt CE, Peters CL. Barbed versus standard sutures for closure in total knee arthroplasty: a multicenter prospective randomized trial. J Arthroplasty 2014; 29: 135-8.

https://doi.org/10.1016/j.arth.2014.01.041

Rubin JP, Hunstad JP, Polynice A, Gusenoff JA, Schoeller T, Dunn R, et al. A multicenter randomized controlled trial comparing absorbable barbed sutures versus conventional absorbable sutures for dermal closure in open surgical procedures. Aesthet Surg J 2014; 34: 272-83. https://doi.org/10.1177/1090820X13519264

Gislason H, Gronbech JE, Soreide O. Burst abdomen and incisional hernia after major gastrointestinal operations--comparison of three closure techniques. Eur J Surg 1995; 161: 349-54.

Seiler CM, Bruckner T, Diener MK, Papyan A, Golcher H, Seidlmayer C, et al. Interrupted or continuous slowly absorbable sutures for closure of primary elective midline abdominal incisions: a multicenter randomized trial (INSECT: ISRCTN24023541). Ann Surg 2009; 249: 576-82. https://doi.org/10.1097/SLA.0b013e31819ec6c8

Figueroa D, Jauk VC, Szychowski JM, Garner R, Biggio JR, Andrews WW, et al. Surgical staples compared with subcuticular suture for skin closure after cesarean delivery: a randomized controlled trial. Obstet Gynecol 2013; 121: 33-8.

https://doi.org/10.1097/AOG.0b013e31827a072c

Mackeen AD, Khalifeh A, Fleisher J, Vogell A, Han C, Sendecki J, et al. Suture compared with staple skin closure after cesarean delivery: a randomized controlled trial. Obstet Gynecol 2014; 123: 1169-75.

https://doi.org/10.1097/AOG.0000000000000227

Basha SL, Rochon ML, Quiñones JN, Coassolo KM, Rust OA, Smulian JC. Randomized controlled trial of wound complication rates of subcuticular suture vs staples for skin closure at cesarean delivery. Am J Obstet Gynecol 2010; 203: 285.e1-8. https://doi.org/10.1016/j.ajog.2010.07.011

Tsujinaka T, Yamamoto K, Fujita J, Endo S, Kawada J, Nakahira S, et al. Subcuticular sutures versus staples for skin closure after open gastrointestinal surgery: a phase 3, multicentre, open-label, randomised controlled trial. Lancet 2013; 382: 1105-12. https://doi.org/10.1016/S0140-6736(13)61780-8

Cameron AE, Parker CJ, Field ES, Gray RC, Wyatt AP. A randomised comparison of polydioxanone (PDS) and polypropylene (Prolene) for abdominal wound closure. Ann R Coll Surg Engl 1987; 69: 113-5.

Dhivya S, Padma VV, Santhini E. Wound dressings - a review. Biomedicine (Taipei) 2015; 5: 22.

https://doi.org/10.7603/s40681-015-0022-9

Shi C, Wang C, Liu H, Li Q, Li R, Zhang Y, et al. Selection of Appropriate Wound Dressing for Various Wounds. Front Bioeng Biotechnol 2020; 8: 182. https://doi.org/10.3389/fbioe.2020.00182

Dumville JC, Gray TA, Walter CJ, Sharp CA, Page T, Macefield R, et al. Dressings for the prevention of surgical site infection. Cochrane Database Syst Rev 2016; 12: Cd003091. https://doi.org/10.1002/14651858

Biffi R, Fattori L, Bertani E, Radice D, Rotmensz N, Misitano P, et al. Surgical site infections following colorectal cancer surgery: a randomized prospective trial comparing common and advanced antimicrobial dressing containing ionic silver. World J Surg Oncol 2012; 10: 94. https://doi.org/10.1186/1477-7819-10-94

Burke NG, Green C, McHugh G, McGolderick N, Kilcoyne C, Kenny P. A prospective randomised study comparing the jubilee dressing method to a standard adhesive dressing for total hip and knee replacements. J Tissue Viability 2012; 21: 84-7. https://doi.org/10.1016/j.jtv.2012.04.002

Dickinson Jennings C, Culver Clark R, Baker JW. A prospective, randomized controlled trial comparing 3 dressing types following sternotomy. Ostomy Wound Manage 2015; 61: 42-9.

Krieger BR, Davis DM, Sanchez JE, Mateka JJ, Nfonsam VN, Frattini JC, et al. The use of silver nylon in preventing surgical site infections following colon and rectal surgery. Dis Colon Rectum 2011; 54: 1014-9.

https://doi.org/10.1097/DCR.0b013e31821c495d

Martín-Trapero C, Martín-Torrijos M, Fernández-Conde L, Torrijos-Torrijos M, Manzano-Martín E, Pacheco-del Cerro JL, et al. [Surgical site infections. Effectiveness of polyhexamethylene biguanide wound dressings]. Enferm Clin 2013; 23: 56-61.

https://doi.org/10.1016/j.enfcli.2013.01.005

Michie DD, Hugill JV. Influence of occlusive and impregnated gauze dressings on incisional healing: a prospective, randomized, controlled study. Ann Plast Surg 1994; 32: 57-64. https://doi.org/10.1097/00000637-199401000-00011

Ozaki CK, Hamdan AD, Barshes NR, Wyers M, Hevelone ND, Belkin M, et al. Prospective, randomized, multi-institutional clinical trial of a silver alginate dressing to reduce lower extremity vascular surgery wound complications. J Vasc Surg 2015; 61: 419-27.e1. https://doi.org/10.1016/j.jvs.2014.07.034

Shinohara T, Yamashita Y, Satoh K, Mikami K, Yamauchi Y, Hoshino S, et al. Prospective evaluation of occlusive hydrocolloid dressing versus conventional gauze dressing regarding the healing effect after abdominal operations: randomized controlled trial. Asian J Surg 2008; 31: 1-5. https://doi.org/10.1016/S1015-9584(08)60046-9

Vogt KC, Uhlyarik M, Schroeder TV. Moist wound healing compared with standard care of treatment of primary closed vascular surgical wounds: a prospective randomized controlled study. Wound Repair Regen 2007; 15: 624-7.

https://doi.org/10.1111/j.1524-475X.2007.00294.x

Wynne R, Botti M, Stedman H, Holsworth L, Harinos M, Flavell O, et al. Effect of three wound dressings on infection, healing comfort, and cost in patients with sternotomy wounds: a randomized trial. Chest 2004; 125: 43-9.

https://doi.org/10.1378/chest.125.1.43

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